Automobile and Martha Johnson Essay Example for Free

Automobile and Martha Johnson Essay Martha Johnson is a mid- class work family. Martha’s goals are buy a car, rent an apartment, stay home and be a full time student, go on vacation, or save the money. The money she has it is from her aunt. Her aunt passed away and left Martha money. I am writing this essay to recommend my option on how Martha Johnson should spend her money. The chose I am going to make is going to help her out how to spend her money. The first goal that Martha has in mind is to buy a car. The advantages is that she has a car that she can use to go to school and go to work. She can also use the car to take her mom to her doctor appointments. Also she can go to the store when she wants to buy something like food, or clothes she will go shopping. The disadvantages is that Martha will have to pay for gas and pay car insurance for the car she buys. She will need to buy a use car not a new car. Also she would need to repair the car if it has any problems with the car. The second goal is that Martha wants to rent an apartment to herself and share it with a roommate also she is going to be a full time student . The advantages is that Martha will have her own place and wont be living with her parents. She will also be close to school and she will be walking instead of driving to school. She will also will be able to finish her career early. Automobile and Martha Johnson. (2017, Feb 08). We have essays on the following topics that may be of interest to you

Chinese popular culture Essay Example | Topics and Well Written Essays - 1500 words

Chinese popular culture - Essay Example To be more specific, this paper will also drill into the deep contrast between college graduates and peasant laborers in terms of the issue. The roles of crime and corruption and social stability and mobility will also be discussed to understand the spread of the issue in China fully. Unemployment and Population The current population of The People’s Republic of China has climbed to 0.01% since last year’s update. To date, the country’s population is approximately 1.354 billion, which is 363.3 people per square mile, basing on its total land area—still the largest in the world (World Population Statistics n.p.). The huge population of China is said to be one of the primary reasons why the problem with unemployment still continues. There are so many advancements in China like the establishment of the world’s largest building called the New Century Global Center, which has an area of 1.7 million square meters alone could provide more job opportunities for fresh graduates and other job seekers (Beam n.p.). However, because of their population density, it is still very difficult to accommodate all of those who are jobless. Aside from large buildings for businesses, there are also amusement and entertainment parks that aid in the country’s tourism industry. ... It is twice as difficult for the peasant laborers coming from poor families in rural areas with less or no education at all because they are most likely discriminated or abused at work compared to educated Chinese (Ren 105). In addition, because of the increase in population, landing a job will even be harder for both the white collared and the peasants in the neoliberal globalization era of PRC. Increase in population will also mean increase in social issues because it will be difficult for the government to balance everything by tending to the issues one by one. Problems in housing, education, and social services are also rooted from overpopulation in China. These problems remain unsolved, and they badly need to be paid attention to by the government. Housing, Education, and Social Services The problem of providing houses to so many people also springs from overpopulation. It will be stressful to provide land areas for families to build houses on that is why most of the families li ve in apartments or other high rise buildings in order to save space. However, not all can afford this type of housing. They may be a really rich country, but there is still poverty in some areas there. In terms of education, many are able to go to school, but there are also unlucky ones who do not have the chance. Thus, the competition becomes biased to those who are more educated when it comes to choosing the people for a job position. In the socialist China, they developed a household registration system that has also a connection with education and benefits. This has created a great divide between the rural and urban China creating different levels of social classes.

INVESTIGATION OF HUMAN DISEASE Essay Example | Topics and Well Written Essays - 1000 words

INVESTIGATION OF HUMAN DISEASE - Essay Example Alternatively, a shorted dystrophin gene may be expressed but still different from normal due to an altered molecular weight. Different probes against different parts of the gene, or alternatively gene sequencing, can be exploited to identify the missing parts. Given the almost asymptomatic patient's status, likely due to the young age, no histological features are expected in muscle biopsies. Therefore, a molecular, i.e. immuno-histochemical, analysis will be necessary. Indeed, immunofluorescence (IF) analysis for dystrophin can confirm the genotyping. In physiological conditions, laminin is localized around all muscle fibers and it appears as circles/polygonal shapes in muscle cross-sections, while it is absent in virtually all muscle fibers in diseased individuals (with the notable exception of possible revertant fibers). Given the invasive nature of this procedure, the IF analysis, which requires more tissue to be collected, will be performed as a second option and only in the pr esence of positive genetic tests. On examining the genomic DNA it was found that exon 52 was absent. (b) Will splicing of exon 51 to 53 produce a functional shortened dystrophin? Explain and justify your decision by using an illustration and text (20%). The splicing of exon 51 to 53 does not produce a shortened dystrophin, since the two exons have different codon boundary. The result of the exon 52 deletion, is thus disruption of the genetic code and the premature stop of protein translation. On the contrary, the splicing of exon 51 to 54 would give rise to a shortened but functional form of dystrophin (see diagram below). In the case presented above, the absence of dystrophin expression and the development of DMD is the diagnosis. Scheme of exon boundary extremities in the dystophin region of interest: After genetic counselling the parents choose to seek help from a specialist in gene therapy. (c) If you were the gene therapy specialist what kind of therapy would you suggest for th e boy. Justify your choice. (20%) I would suggest an exon skipping approach with antisense oligonucleotides (AON) aimed to skip exon 53. The loss of the latter in addition to the congenital loss of exon 52 will likely allow to rescue the expression of an almost normal dystrophin, which lacks only two of the repeated motifs that constitute the central body of the protein. Exon skipping has recently been proven an efficient therapeutic approach in large animals (dogs) affected by muscular dystrophy (Yokoda, 2011). PART II (50% total) 1) The picture above shows a family with an inherited disorder. All affected individuals are tall and thin, with long fingers and toes. a) What would a genetic counselor be able to tell an affected individual about the mode of inheritance and the serious complications associated with the disorder (10%) The phenotype of the people in the picture is compatible with the diagnosis of the Marfan. In fact, people with Marfan syndrome tend to be unusually tall, with long, thin fingers. It is inherited as a dominant trait, thus people who have inherited one affected gene from either parent will have Marfan syndrome. This may explain the high penetrance of the disease into a group of individuals, likely members of the same family in the pcture. b) Explain the molecular basis of the condition (15%)